SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

       Date of Report (Date of earliest event reported): January 28, 2003

                             ----------------------

                         COMMISSION FILE NUMBER 1-12584


                                                                                  
DELAWARE                            SHEFFIELD PHARMACEUTICALS, INC.                     13-3808303
(State of other jurisdiction of     (Exact name of registrant as specified              (I.R.S. Employer
incorporation or organization)      in its charter)                                     Identification No.)


3136 Winton Road South, Suite 201, Rochester, New York          14623
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       (Address of principal executive officers)              (Zip Code)

        Registrant's telephone number, including area code (585) 292-0310
                             ----------------------

  14528 South Outer Forty Road, Suite 205, St. Louis, Missouri    63017
  ------------------------------------------------------          -----
         (Former name or former address, if changed since last report)






ITEM 5.  OTHER EVENTS

         On January 24, 2003, Sheffield Pharmaceuticals, Inc., a Delaware
corporation, issued a press release, a copy of which is attached hereto as
Exhibit 99.3 and is incorporated herein by reference.

ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS

(c)      Exhibits

Exhibit Number    Description

       99.3       Press Release dated January 24, 2003 issued by Sheffield
                  Pharmaceuticals, Inc.


                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                SHEFFIELD PHARMACEUTICALS, INC.


Dated:  January 28, 2003        By: /s/ Scott A. Hoffmann
                                    -------------------------------------
                                Scott A. Hoffmann
                                Vice President and Chief Financial Officer