Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  SHERMAN JEFFREY W
2. Date of Event Requiring Statement (Month/Day/Year)
07/28/2011
3. Issuer Name and Ticker or Trading Symbol
HORIZON PHARMA, INC. [HZNP]
(Last)
(First)
(Middle)
C/O HORIZON PHARMA, INC., 1033 SKOKIE BLVD., SUITE 355
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
EVP & Chief Medical Officer
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NORTHBROOK, IL 60062
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy)   (1) 06/22/2019 Common Stock 46,335 $ 13.47 D  
Employee Stock Option (Right to Buy)   (2) 02/02/2020 Common Stock 47,654 $ 5.2 D  
Employee Stock Option (Right to Buy)   (3) 06/05/2020 Common Stock 42,295 $ 12.94 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
SHERMAN JEFFREY W
C/O HORIZON PHARMA, INC.
1033 SKOKIE BLVD., SUITE 355
NORTHBROOK, IL 60062
      EVP & Chief Medical Officer  

Signatures

/s/ Jeffrey W. Sherman 07/28/2011
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) 25% of the Shares subject to the Option vest and become exercisable on June 29, 2010, and 1/48th of the Shares vest in equal monthly installments thereafter.
(2) 25% of the Shares subject to the Option vest and become exercisable on February 3, 2011, and 1/48th of the Shares vest in equal monthly installments thereafter.
(3) 25% of the Shares subject to the Option vest and become exercisable on June 29, 2010, and 1/48th of the Shares vest in equal monthly installments thereafter.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

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