UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 4 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. -------------------------------------------------------------------------------- 1. Name and Address of Reporting Person(s) Essig, Stuart M. -------------------------------------------------------------------------------- (Last) (First) (Middle) -------------------------------------------------------------------------------- 311 Enterprise Drive -------------------------------------------------------------------------------- (Street) Plainsboro, New Jersey 08536 -------------------------------------------------------------------------------- (City) (State) (Zip) -------------------------------------------------------------------------------- 2. Issuer Name and Ticker or Trading Symbol Integra LifeSciences Holdings Corp. (IART) -------------------------------------------------------------------------------- 3. I.R.S. Identification Number of Reporting Person, if an entity (Voluntary) -------------------------------------------------------------------------------- 4. Statement for Month/Day/Year 03/18/2003 -------------------------------------------------------------------------------- 5. If Amendment, Date of Original (Month/Day/Year) -------------------------------------------------------------------------------- 6. Relationship of Reporting Person(s) to Issuer (Check all applicable) [X] Director [ ] 10% Owner [X] Officer (give title below) [ ] Other (specify below) President and Chief Executive Officer -------------------------------------------------------------------------------- 7. Individual or Joint/Group Filing (Check Applicable Line) [X] Form filed by One Reporting Person [ ] Form filed by More than One Reporting Person -------------------------------------------------------------------------------- Table I Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned ------------------------------------------------------------------------------------------------------------------------------------ 1)Title of Security 2)Trans- 3.Trans- 4.Securities Acquired(A) 5)Amount of 6) 7)Nature of action action or Disposed of (D) Securities Indirect Date Code A Beneficially D Beneficial (Month/ or Owned at or Ownership Day/Year) Code V Amount D Price End of Month I ------------------------------------------------------------------------------------------------------------------------------------ Common Stock 03/18/03 M 161,000 A $5.8750 D Direct Common Stock 03/18/03 S 161,000 D $22.0000 D Direct Common Stock 03/18/03 M 39,000 A $5.8750 D Direct Common Stock 03/18/03 S 39,000 D $22.0000 71,261 D Direct Table II (PART 1) Derivative Securities Acquired, Disposed of, or Beneficially Owned (Columns 1 through 6) ------------------------------------------------------------------------------------------------------------------------------------ 1)Title of Derivative 2)Conversion 3)Trans- 4)Trans- 5)Number of Derivative 6)Date Exercisable and Security or Exercise action action Securities Acquired (A) Expiration Date Price of Date Code or Disposed of (D) Derivative Security Code V A D Exercisable Expiration ------------------------------------------------------------------------------------------------------------------------------------ Non-Qualified Stock Option $5.8750 03/18/03 M 39,000 (1) 12/31/05 (right to buy) Non-Qualified Stock Option $5.8750 03/18/03 M 161,000 (1) 12/26/07 (right to buy) (2) Table II (PART 2) Derivative Securities Acquired, Disposed of, or Beneficially Owned (Columns 1,3 and 7 through 11) ------------------------------------------------------------------------------------------------------------------------------------ 1)Title of Derivative 3)Trans- 7)Title and Amount 8)Price 9)Number of 10) 11)Nature of Security action of Underlying of Deri- Derivative Indirect Date Securities vative Securities D Beneficial Amount or Security Beneficially or Ownership Number of Owned at I - Title Shares End of Month ------------------------------------------------------------------------------------------------------------------------------------ Non-Qualified Stock Option 03/18/03 Common Stock 39,000 1,875 D Direct (right to buy) Non-Qualified Stock Option 03/18/03 Common Stock 161,000 339,000 D Direct (right to buy) (2) Explanation of Responses: (1) 25% of the options vest one year after the grant date, with the remaining 75% vesting monthly thereafter over 36 months (2) Granted on December 27, 1997 SIGNATURE OF REPORTING PERSON /S/ Essig, Stuart M. DATE 03/18/03