Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Sardesai Niranjan
2. Date of Event Requiring Statement (Month/Day/Year)
06/01/2009
3. Issuer Name and Ticker or Trading Symbol
INOVIO BIOMEDICAL CORP [INO]
(Last)
(First)
(Middle)
11494 SORRENTO VALLEY ROAD
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Sr. VP Research & Development
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SAN DIEGO, CA 92121
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Inovio Biomedical Corporation Common Stock Option (1) (2) (3) 08/28/2006 08/28/2016 Inovio Biomedical Corporation Common Stock 132,462 $ 1.53 D  
Inovio Biomedical Corporation Common Stock Option (1) (2) (4) 01/05/2007 01/05/2017 Inovio Biomedical Corporation Common Stock 24,530 $ 1.53 D  
Inovio Biomedical Corporation Common Stock Option (1) (2) (5) 01/18/2007 01/18/2017 Inovio Biomedical Corporation Common Stock 14,718 $ 1.53 D  
Inovio Biomedical Corporation Common Stock Option (1) (2) (6) 11/01/2007 11/01/2017 Inovio Biomedical Corporation Common Stock 73,590 $ 1.53 D  
Inovio Biomedical Corporation Common Stock Option (1) (2) (7) 09/12/2008 09/12/2018 Inovio Biomedical Corporation Common Stock 29,436 $ 1.53 D  
Inovio Biomedical Corporation Common Stock Option (1) (2) (8) 09/12/2008 09/12/2018 Inovio Biomedical Corporation Common Stock 19,624 $ 1.53 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Sardesai Niranjan
11494 SORRENTO VALLEY ROAD
SAN DIEGO, CA 92121
      Sr. VP Research & Development  

Signatures

/s/ Niranjan Sardesai 06/01/2009
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Issued upon assumption of outstanding VGX Pharmaceutical Inc. stock options in conjunction with closing of the business combination transaction between VGX Pharmaceuticals and Inovio Biomedical Corporation on June 1, 2009.
(2) The vesting schedule is based on the original grant.
(3) 14,718 shares vested immediately, 39,248 shares vested on August 28, 2007, 39,248 shares will vest on August 28, 2009 and 39,248 shares will vest August 28, 2010.
(4) The first tranche of 8,176 shares vested on January 5, 2008, the second tranche of 8,176 shares vested on January 5, 2009, and the third tranche of 8,176 shares will vest January 5, 2010.
(5) The first tranche of 4,906 shares vested on January 18, 2008, the second tranche of 4,906 shares vested on January 18, 2009, and the third tranche of 4,906 shares will vest January 18, 2010.
(6) 29,436 shares vested immediately, 14,718 shares vested on November 1, 2008, 14,718 shares will vest on November 1, 2009 and 14,718 shares will vest November 1, 2010.
(7) The first tranche of 14,718 shares will vest on September 12, 2009, the second tranche of 14,718 shares will vest on September 12, 2010.
(8) The first tranche of 6,541 shares will vest on September 12, 2009, the second tranche of 6,541 shares will vest on September 12, 2010, and the third tranche of 6,541 shares will vest September 12, 2011.

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